In the heydays of the imperial powers; Tsarist Russia tried in vain to get an opening into the warm waters somewhere in the Arabian Sea but the British colonial masters realized this emerging threat to their colonial possession in south Asia and hence prevented Russians to cross the Oxus southward, this was known as “the Great Game”. Pakistan was kept as the border land on the western frontier of India, yet the worst sufferers were the people of Central Asia who were isolated from the rest of the world and their countries were developed as backyard garden of Russia (Dani, A, H, 1996, 23). History reveals that Pakistan have had close economic ties with the region. The dissolution of USSR in 1991, not only provided independence to Central Asian states, but gave opportunity to open themselves in the world through Pakistan via land routes and sea routes. The main focus of this paper is to highlight Pakistan’s prospects and challenges for Central Asian states.