The purpose of this study is to examine socioeconomic and demographic factors affecting married women work participation in Southern Punjab. Primary data from 474 married women is gathered from three divisions i.e. Bahawalpur, Multan and DG Khan through random sampling technique. The results of correlation matrix confirm that the econometric model is free from the problem of Multicollinearity. The results of Logistic regression concludes that age, education, decision to work, distance of workplace and family setup are declared as motivating factors for married women’s work participation while square of age, distance of health unit, residence and husband’s job are confirmed as de-motivating factors for married women’s work participation in economic activities.